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Effects of acidity on the size of polyaniline-poly(sodium 4-styrenesulfonate) composite particles and the stability of corresponding colloids in water

✍ Scribed by Ligui Li; Linhui Ferng; Yen Wei; Catherine Yang; Hai-Feng Ji

Book ID: 113689242
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 987 KB
Volume: 381
Category: Article
ISSN: 0021-9797
DOI: 10.1016/j.jcis.2012.05.004

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## Abstract Encapsulation of proteins in poly(lactic‐co‐glycolic) acid (PLGA) microspheres by the water‐in‐oil‐in‐water (w/o/w) technique is very challenging because of the inherent physical instability of proteins. In particular, exposure of proteins to the first water‐in‐oil emulsion causes unwan