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Effects of a sinus node inhibitor on the normal and failing rabbit heart

โœ Scribed by K. H. Ryu; N. Tanaka; J. Ross


Publisher
Springer
Year
1996
Tongue
English
Weight
717 KB
Volume
91
Category
Article
ISSN
0300-8428

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Mechanical effects of ET-1 in cardiomyoc
โœ Elizabeth J. Kelso; Robert F. Geraghty; Barbara J. McDermott; Elisabeth R. Trimb ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer ๐ŸŒ English โš– 687 KB

Endothelin (ET-1) is found at elevated concentrations in the plasma of patients with heart failure and in animal models of cardiomyopathy. The peptide is a potent positive inotropic agent, the effects of which are mediated by increases in cytosolic Ca2+ in cardiomyocytes. The object of this study wa