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Effects of a prostaglandin EP4 agonist, ONO-4819, and risedronate on trabecular microstructure and bone strength in mature ovariectomized rats

✍ Scribed by Masako Ito; Keiji Nakayama; Akira Konaka; Kiyoto Sakata; Kyoji Ikeda; Takayuki Maruyama

Book ID: 116319661
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 308 KB
Volume: 39
Category: Article
ISSN: 8756-3282
DOI: 10.1016/j.bone.2006.02.054

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## Abstract The agonist of the prostaglandin EP4 receptor can increase bone density in osteoporosis. Using ovariectomized (OVX) and sham‐operated (SO) rats, the effects of the EP4 receptor agonist, ONO‐4819, and hydroxyapatite (HA) on implant‐bone fixation in implants with a rough surface were inve

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