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Effects of a novel tylophorine analog on collagen-induced arthritis through inhibition of the innate immune response

✍ Scribed by Xin You; Meng Pan; Wenli Gao; Her-Shyong Shiah; Jian Tao; Dongqing Zhang; Fotios Koumpouras; Shuang Wang; Hongyu Zhao; Joseph A. Madri; David Baker; Yung-Chi Cheng; Zhinan Yin

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
230 KB
Volume
54
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To apply and analyze the mechanisms of action of dimethyldioctadecylammonium bromide (DDA), a powerful adjuvant that does not have the side effects of the conventionally used Freund's adjuvants, in proteoglycan‐induced arthritis (PGIA) and collagen‐induced arthritis (CIA).