✦ LIBER ✦

Effects of a low-voltage static electric field on energy metabolism in astrocytes

✍ Scribed by Rong Huang; Liang Peng; Leif Hertz

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 65 KB
Volume: 18
Category: Article
ISSN: 0197-8462
DOI: 10.1002/(sici)1521-186x(1997)18:1<77::aid-bem11>3.0.co;2-n

No coin nor oath required. For personal study only.

✦ Synopsis

Mouse astrocytes (glial cells) in primary cultures were exposed to a low-voltage static DC electric field with no current flow and thus with no generation of magnetic fields. The electric field altered the rate of glycolysis, measured by 2-deoxyglucose accumulation. The magnitude and direction of this effect depended on the polarization of the field and the applied voltage. The maximum effect was an increase of approximately 30%, which occurred with field across the cells at an intensity that can be calculated to be 0.3 mV/cm or less. Reversal of the polarization converted the stimulation to a small but statistically significant inhibition.

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