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Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes

โœ Scribed by Phong Lan Thao Tran; Antonella Virgilio; Veronica Esposito; Giuseppe Citarella; Jean-Louis Mergny; Aldo Galeone

Book ID
116309323
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
978 KB
Volume
93
Category
Article
ISSN
0300-9084

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7-Deazapurine Oligodeoxyribonucleotides:
7-Deazapurine Oligodeoxyribonucleotides: The effects of 7-deaza-8-methylguanine on dna structure and stability
โœ Frank Seela; Yaoming Chen; Cathrin Mittelbach ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 769 KB

Oligodeoxyribonucleotides containing 7-deaza-2'-deoxy-8-methylguanosine (mRc7G,; 2b) were prepared. For this purpose, the phosphonate 3a and the phosphoramidite 3b were synthesized and employed in solidphase oligodeoxyribonucleotide synthesis. The structures and the thermodynamic data of duplex form