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Effects of 8-hydroxy-GTP and 2-hydroxy-ATP on in vitro transcription

✍ Scribed by Hiroyuki Kamiya; Akihiro Suzuki; Kazuaki Kawai; Hiroshi Kasai; Hideyoshi Harashima

Book ID
113630361
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
215 KB
Volume
43
Category
Article
ISSN
0891-5849

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To study the possible involvement of reactive oxygen species (ROS) in the tumor biology of human renal-cell carcinoma (RCC), we analyzed 35 cases of RCC for 2 parameters of oxidative damage: 8-hydroxy-2'-deoxyguanosine (8-OHdG), a mutation-prone DNA-base-modified product, was measured by means of hi