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Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres

✍ Scribed by Sherratt, R. M.; Bostock, H.; Sears, T. A.


Book ID
109717533
Publisher
Nature Publishing Group
Year
1980
Tongue
English
Weight
359 KB
Volume
283
Category
Article
ISSN
0028-0836

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Facilitatory effects of 4-aminopyridine
✍ Yong I. Kim; Marcia M. Goldner; Dr. Donald B. Sanders πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 English βš– 604 KB

## Abstract The effects of 4‐aminopyridine (4‐AP) on neuromuscular transmission were studied in vitro in the rat flexor digitorum longus muscles. 4‐AP produced dose‐dependent increases in endplate potential (EPP) amplitude, in rise time to peak, and in the average number of acetylcholine quanta rel