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Effects of 18 weeks of daily melatonin injection on reproduction and temperature regulation in the mouse,Peromyscus leucopus

✍ Scribed by Heath, Harley W. ;Lynch, G. Robert

Publisher: John Wiley and Sons
Year: 1981
Tongue: English
Weight: 246 KB
Volume: 216
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1402160122

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✦ Synopsis

Abstract

Mice injected daily with 50 μg of melatonin, 12 hr after lights on, for 18 weeks, underwent gonadal regression after 4–7 weeks and reproductive recrudescence after 15 weeks. Most treated animals molted to a winter pelt after 9–11 weeks of injections, and 2 of the 10 mice experienced bouts of daily torpor after 14 weeks.

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## Abstract Quantitative comparison of pinealocyte ultrastructure in 3‐month‐old and 28‐month‐old male white‐footed mice (__Peromyscus leucopus__) revealed decreases both in the area of the Golgi apparatus and in the number of dense‐core vesicles. In contrast, no differences between these two age g