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Effects and Metabolism of Steroid Hormones in Human Neuroblastoma Cells

✍ Scribed by Roberto Maggi; Angelo Poletti; Luiz A. Casulari; Federica Pimpinelli; Flavio Piva; Maria R. Zanisi; Luciano Martini

Book ID
117214003
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
187 KB
Volume
63
Category
Article
ISSN
0039-128X

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## Abstract The IMP dehydrogenase inhibitor, tiazofurin (TR)‐2‐β‐D‐ribofuranosylthiazole‐4‐carboxamide, which exhibited oncolytic activity in patients with chronic myelogenous leukaemia (CML) in blast crisis was found to inhibit the growth of human neuroblastoma SK‐N‐SH cells with an IC~50~ of 4.2