Background: Tumor necrosis factor (TNF)-like protein 1A (TL1A) is a member of the TNF superfamily and contributes to the pathogenesis of Crohn's disease (CD) by stimulating T-helper (Th) 1 cells. In addition to Th1, recent studies have focused on the role of Th17 cells in the pathogenesis of CD. Her
β¦ LIBER β¦
Effector Th-1 Cells with Cytotoxic Function in the Intestinal Lamina Propria of Patients with Crohn's Disease
β Scribed by P. Mariani; A. Bachetoni; M. D'Alessandro; D. Lomanto; P. Mazzocchi; V. Speranza
- Book ID
- 110225471
- Publisher
- Springer US
- Year
- 2000
- Tongue
- English
- Weight
- 89 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0163-2116
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## Background: The leukocyte function associated antigen-1 (LFA-1) intracellular adhesion molecule-1 pathway is presumed to play a pivotal role in the perpetuation of inflammatory bowel disease. We aimed to elucidate the effect of 2 different therapies on LFA-1 expression in patients with Crohn's