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Effector and memory CD8+ T cell differentiation: toward a molecular understanding of fate determination

โœ Scribed by Gabrielle T Belz; Axel Kallies


Book ID
108099668
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
237 KB
Volume
22
Category
Article
ISSN
0952-7915

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โœ Selina J. Keppler; Kerstin Theil; Smiljka Vucikuja; Peter Aichele ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 497 KB ๐Ÿ‘ 1 views

## Abstract To study the role of ILโ€12 as a third signal for Tโ€cell activation and differentiation __in vivo__, direct ILโ€12 signaling to CD8^+^ T cells was analyzed in bacterial and viral infections using the P14 Tโ€cell adoptive transfer model with CD8^+^ T cells that lack the ILโ€12 receptor. Resu