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Effectiveness of haemofiltration in valproic acid intoxication

✍ Scribed by JG van Keulen; JAE van Wijk; DJ Touw; J van der Deure; DG Markhorst; RJBJ Gemke


Book ID
114812978
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
59 KB
Volume
90
Category
Article
ISSN
0803-5253

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Choleretic effect of valproic acid in th
✍ John B. Watkins; Curtis D. Klaassen πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 724 KB

Valproic acid (WA) is an anticonvulsant agent which produced marked choleresis in the rat. Bile flow rate increased from 50 to 60 pl per min per kg to 120 to 145 p1 per min per kg immediately after i.v. injection of VPA (37.5 to 150 mg per kg; 2 ml per kg) in male Sprague-Dawley rats. The duration o