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Effectiveness of a traditional Chinese medicine, Wulingsan, in suppressing the development of nephrocalcinosis induced by a high phosphorus diet in young rats

✍ Scribed by Qiao-ling Liu; S. Sato; Teruko Kishikawa; Hiroshi Matsuzaki; Nobuaki Yamanaka

Publisher
Springer
Year
2001
Tongue
English
Weight
551 KB
Volume
34
Category
Article
ISSN
0918-4287

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## Abstract The effect of obesity induced by a high‐fat diet on the pharmacokinetics (PK) of nelfinavir (NFV) was investigated, focusing on the change of distribution and elimination caused by dyslipidemia and hepatic steatosis. The plasma unbound fraction (__f__~u~) of NFV in obese rats (0.61Β±0.0