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Effective treatment of murine cytomegalovirus infections with methylenecyclopropane analogues of nucleosides

✍ Scribed by Rachel J Rybak; Jiri Zemlicka; Yao-Ling Qiu; Caroll B Hartline; Earl R Kern

Book ID: 114145241
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 152 KB
Volume: 43
Category: Article
ISSN: 0166-3542
DOI: 10.1016/s0166-3542(99)00043-1

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## Abstract A chemically synthesized lipid A subunit analogue, GLA‐60 (2‐deoxy‐4–0‐phosphono‐2‐[(3R)‐3‐hydroxytetradecanamido] ‐ 3 ‐ 0‐ [(3R) ‐ 3 ‐tetradecanoyloxytetradecanoyl]‐D‐glucose), has many of the activities of endotoxins but little, if any, toxicity. We investigated the protective activit