𝔖 Bobbio Scriptorium
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Effective Therapy for Advanced Gastrointestinal Stromal Tumors

✍ Scribed by Collins, Chris G. ;O'Sullivan, Gerald C. ;Shanahan, Fergus

Book ID
119426856
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
58 KB
Volume
124
Category
Article
ISSN
0016-5085

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πŸ“œ SIMILAR VOLUMES

Systemic therapy for advanced gastrointe
Systemic therapy for advanced gastrointestinal stromal tumors: Beyond imatinib
✍ Edward J. Kim; Mark M. Zalupski πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 88 KB

## Abstract Progression on first‐line therapy with imatinib in gastrointestinal stromal tumors (GIST) is caused by either initial resistance or more often a secondary mutation in tyrosine kinases KIT or PDGFR. Therapies in development for imatinib‐resistant GIST include agents that target KIT/PDGFR