In this Letter, we report a novel approach to the preparation of 3-anilino-pyrazin-2(1H)-ones and 3-anilino-quinoxalin-2(1H)-ones from the corresponding 3-halo pyrazin-2-amines and 3-haloquinoxalin-2-amines, using a microwave-mediated Smiles rearrangement.
β¦ LIBER β¦
Effective synthesis of 3,5-diaryl-(1H)-pyrazin-2-ones via microwave mediated ring closure
β Scribed by Johannes, Eugen; Horbert, Rebecca; Schlosser, Joachim; Schmidt, Dorian; Peifer, Christian
- Book ID
- 120371116
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- French
- Weight
- 365 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4039
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