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Effective production of a human monoclonal antibody against tetanus toxoid by selection of high productivity clones of a heterohybridoma

โœ Scribed by Kazuaki Kitano; Keiji Iwamoto; Yasushi Shintani; Shun-ichi Akiyama

Book ID
118901344
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
637 KB
Volume
109
Category
Article
ISSN
0022-1759

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The production of human monoclonal antibodies for therapeutic use is of increasing importance for treatment of viral infections such as AIDS. As human x mouse heterohybridomas rarely reach the growth rates and cell specific production rates of mouse hybridomas the transfection of standard cell lines