Improved efficacy of dendritic cell vacc
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Francesca Fallarino; Catherine Uyttenhove; Thierry Boon; Thomas F. Gajewski
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Article
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1999
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John Wiley and Sons
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French
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The well-characterized P815 tumor model was used to optimize anti-tumor immunization approaches in mice. Tumor peptides derived from antigens P198 or P1A were targeted to antigen-presenting cells (APC) by ex vivo pulsing. Initial experiments with irradiated pulsed splenic dendritic cells (sDC) injec