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Effective glucuronidation of 6α-hydroxylated bile acids by human hepatic and renal microsomes

✍ Scribed by Michel PARQUET; Marcia PESSAH; Edmond SACQUET; Colette SALVAT; Annie RAIZMAN


Book ID
115125569
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
673 KB
Volume
171
Category
Article
ISSN
1432-1327

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In a search for enzymes involved in the formation of bile acids from 27-hydroxycholesterol in humans, the metabolism of this and other side-chain oxygenated steroids was studied in human liver microsomes and mitochondria. The microsomal fraction contained enzyme(s) catalyzing 7a-hydroxylation of 27-