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Effective cotranslational folding of firefly luciferase without chaperones of the Hsp70 family

✍ Scribed by Maxim S. Svetlov; Aigar Kommer; Vyacheslav A. Kolb; Alexander S. Spirin


Book ID
111752600
Publisher
Cold Spring Harbor Laboratory Press
Year
2006
Tongue
English
Weight
171 KB
Volume
15
Category
Article
ISSN
0961-8368

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## Abstract During mild heat–stress, a native thermolabile polypeptide may partially unfold and transiently expose water‐avoiding hydrophobic segments that readily tend to associate into a stable misfolded species, rich in intra‐molecular non‐native beta‐sheet structures. When the concentration of