Effect on memory processes of anti-vasopressin serum microinjected into the dorsal raphe nucleus: The role of catecholaminergic neurotransmission

✍ Scribed by G. L. Kovács; L. Vécsei; L. Medve; G. Telegdy

• Book ID: 104676686
• Publisher: Springer-Verlag
• Year: 1980
• Tongue: English
• Weight: 656 KB
• Volume: 38
• Category: Article
• ISSN: 0014-4819
• DOI: 10.1007/bf00236656

✦ Synopsis

Anti-arginine8-vasopressin serum was microinjected into the mesencephalic dorsal raphe nucleus immediately after the learning trial, in a one-trial learning passive avoidance reaction. The treatment attenuated passive avoidance behavior 24 h after treatment, suggesting a role of the endogenous vasopressin of this area in memory processes. On the other hand, the antiserum did not influence passive avoidance behavior if 6-hydroxydopamine was microinjected into the raphe region. The data suggest that the antiserum may have primarily interacted with catecholaminergic terminals, which enter the dorsal raphe nucleus.