Effect of β-N-oxalyl-L-α, β-diaminopropionic acid on glutamate uptake by synaptosomes
✍ Scribed by LAKSHMANAN, J.; PADMANABAN, G.
- Book ID
- 109690578
- Publisher
- Nature Publishing Group
- Year
- 1974
- Tongue
- English
- Weight
- 311 KB
- Volume
- 249
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/249469a0
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📜 SIMILAR VOLUMES
## Abstract An amperometric method for the determination of the neurotoxic amino acid β‐__N__‐oxalyl‐L‐α,β‐diaminopropionic acid (β‐ODAP) using a screen printed carbon electrode (SPCE) is reported. The electrode material was bulk‐modified with manganese dioxide and used as a detector in flow inject
p-N-Oxalyl-L-a$-diaminopropionic acid (P-L-ODAP) is thought to be the causative agent in lathyrism due to its neuroexcitatory and neurotoxic properties. We have recently reported that P-L-ODAF' is also gliotoxic at high concentrations (Bridges et al.: Brain Res 561:262, 1991). Evidence is now presen