Effect of β-cyclodextrin on mucochloric acid and 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
✍ Scribed by Ieva R. Politzer; Kathleen T. Crago; Wendy Benjamin; Jocelyn Joseph; Keith Amos; W. Emile Coleman
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 416 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0090-4341
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract 3‐Chloro‐4‐(dichloromethyl)‐5‐hydroxy‐2(5__H__)‐furanone (MX) is a genotoxic chlorination by‐product in drinking water. There is some evidence that it has developmental toxic effects in vitro but its potential to cause developmental effects in vivo is not known. The developmental effect
## Abstract 3,4‐Dichloro‐2(5__H__)‐furanone, which has been prepared efficiently from mucochloric acid, has been transformed selectively into 4‐aryl‐3‐chloro‐2(5__H__)‐furanones either by Suzuki‐ or Stille‐type reactions. These monochloro derivatives have been used as precursors either to (__Z__)‐4