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Effect of β-cyclodextrin on disposition of hexobarbital and phenobarbital in mice

✍ Scribed by O. Shirakura; N. Nambu; T. Nagai

Publisher
Springer Netherlands
Year
1984
Tongue
English
Weight
508 KB
Volume
2
Category
Article
ISSN
0923-0750

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We investigated the effect of pregnancy on nitrofurantoin (NFT) disposition in wild-type and Bcrp1(-/-) mice. Pregnant and non-pregnant mice were administered NFT intravenously (5 mg/kg) or orally (10 mg/kg). Blood samples were collected at various times (5-60 min) after drug administration, plasma