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Effect of YM 9429, a potent teratogen, on cholesterol biosynthesis in cultured cells and rat liver microsomes

โœ Scribed by Akira Honda; G.Stephen Tint; Sarah Shefer; Ashok K. Batta; Megumi Honda; Gerald Salen

Book ID
117213764
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
445 KB
Volume
61
Category
Article
ISSN
0039-128X

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โœ Akira Honda; Gerald Salen; Lien B. Nguyen; Guorong Xu; G. Stephen Tint; Ashok K. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 103 KB

Cytosolic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase catalyzes the formation of HMG-CoA, the substrate for the rate-controlling enzyme in the cholesterol biosynthetic pathway. To explore the regulation in liver, we developed a new, accurate, and reliable reversed-phase ion-pair chromat