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Effect of Wool Waxes and Wool Wax Derivatives on the Release of Some Antibiotics from a Hydrocarbon Base

✍ Scribed by El-Nimr, A. E. ;Salama, H. A. ;Kassem, M. A.

Publisher: John Wiley and Sons
Year: 1983
Weight: 192 KB
Volume: 85
Category: Article
ISSN: 0931-5985
DOI: 10.1002/lipi.19830850808

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✦ Synopsis

a m a a n d M . A . K a s s e m '

The rate of diffusion of chloramphenicol and tetracycline-HCI from white petrolatum wasfoundtoincreaseinthepresenceofeitherwoolwaxesorwool wax derivatives; the effect being more pronounced in conjunction with the latter group. Forbothantibiotics,thereleasingproperties were found tokeep increasing with increasing wax (local Merino) concentration; however, for each antibiotic the increase followsaspecialpattem.Therateof1iberationof the antibiotics could not be correlated to any investigated individual physico-chemical property of the waxes or wax derivatives.

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