Effect of water coordination on competition betweenπand non-πcation binding sites in aromatic amino acids:l-phenylalanine,l-tyrosine, andl-tryptophan Li+, Na+, and K+complexes

Competition between π and Non-π Cation-B

Competition between π and Non-π Cation-Binding Sites in Aromatic Amino Acids: A Theoretical Study of Alkali Metal Cation (Li+, Na+, K+)–Phenylalanine Complexes

✍ Fung Ming Siu; Ngai Ling Ma; Chun Wai Tsang 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB

## Abstract To understand the cation–π interaction in aromatic amino acids and peptides, the binding of M^+^ (where M^+^ = Li^+^, Na^+^, and K^+^) to phenylalanine (Phe) is studied at the best level of density functional theory reported so far. The different modes of M^+^ binding show the same orde