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Effect of water activity on production of β-lactam antibiotics byStreptomyces clavuligerusin submerged culture

✍ Scribed by Cochet, N. ;Demain, A.L.

Book ID
108837277
Publisher
Wiley (Blackwell Publishing)
Year
1996
Tongue
English
Weight
437 KB
Volume
80
Category
Article
ISSN
0021-8847

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In surface cultures of Streptomyces cyaneus var. viridochromogenes, NaCl depressed water activity (a w) without supporting growth. Reducing a w from 0.987 to 0.951 led to 3- and 4-fold increases in intracellular and extracellular phenol oxidase activities, respectively.