𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of water activity on enzymatic synthesis of cephalexin

✍ Scribed by Chang K. Hyun; Jung H. Kim; Young J. Kim


Book ID
105045952
Publisher
Springer Netherlands
Year
1989
Tongue
English
Weight
203 KB
Volume
11
Category
Article
ISSN
0141-5492

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Enhancement effect of polyethylene glyco
✍ Chang K. Hyun; Joon H. Choi; Jung H. Kim; Dewey D. Y. Ryu πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 424 KB πŸ‘ 2 views

In an enzymatic synthesis of cephalexin (CEX) using an acylase from Xanthomonas citri, the effect of polyethylene glycol (PEG) on the synthetic reaction of Zamino-3-deacetoxycephalosporanic acid (FADCA) and D-alpha-phenylglycine methyl ester (PGM) to CEX was investigated. The addition of PEG (MW 300

Enzymatic synthesis of cephalexin in aqu
✍ Dong-Zhi Wei; Jian-Hang Zhu; Xue-Jun Cao πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 English βš– 77 KB

Cephalexin was synthesized in aqueous two-phase systems (ATPSs) by using penicillin G acylase (PGA) (penicillin amidohydrolase, EC3.5.1.11) as a catalyst and 7-aminodeacetoxicephalosporanic acid (7-ADCA) and phenylglycine methyl ester (PGME) as substrates. In the ATPS composed of 20% (w/w) PEG 400 a

A two-step, one-pot enzymatic synthesis
✍ Margreth A. Wegman; Luuk M. van Langen; Fred van Rantwijk; Roger A. Sheldon πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 113 KB πŸ‘ 2 views

## Abstract A cascade of two enzymatic transformations is employed in a one‐pot synthesis of cephalexin. The nitrile hydratase (from __R. rhodochrous__ MAWE)‐catalyzed hydration of D‐phenylglycine nitrile to the corresponding amide was combined with the penicillin G acylase (penicillin amidohydrola