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Effect of vitamin a on bone resorption: Evidence for direct stimulation of isolated chicken osteoclasts by retinol and retinoic acid

✍ Scribed by Richard O.C. Oreffo; A. Teti; J.T. Triffitt; M.J.O. Francis; A. Carano; Dr. Zambonin A. Zallone

Book ID: 112118322
Publisher: American Society for Bone and Mineral Research
Year: 2009
Tongue: English
Weight: 936 KB
Volume: 3
Category: Article
ISSN: 0884-0431
DOI: 10.1002/jbmr.5650030213

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## Abstract Osteoclast activity is thought to be regulated by calcitonin, as well as by the level of ionised calcium generated locally as a result of bone resorption. The exposure of isolated osteoclasts to elevated ambient calcium levels has been shown to lower resorptive activity and to reduce ra