𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of verapamil on daunorubicin accumulation in human leukemic cells with different levels of MDR1 gene expression

✍ Scribed by Astrid Gruber; Bernd Briese; Iréne Areström; Sigurd Vitols; Magnus Björkholm; Curt Peterson


Book ID
113239716
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
469 KB
Volume
17
Category
Article
ISSN
0145-2126

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Effects of cyclosporin a and verapamil o
✍ M. H. Silbermann; A. W. M. Boersma; A. L. W. Jamssen; R. J. Scheper; H. Herweije 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 French ⚖ 961 KB

## Multidrug -resistance (MDR) is characterized by the presence of a 170 kDa glycoprotein (P-glycoprotein) in the plasma membrane. P-glycoprotein is thought to act as an efflux pump, leading to reduced drug accumulation in MDR cells. This defect in drug accumulation can be overcome by membrane tra