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Effect of varying the exposure and3H-thymidine labeling period upon the outcome of the primary hepatocyte DNA repair assay

✍ Scribed by T. R. Barfknecht; D. J. Mecca; R. W. Naismith


Publisher
Springer
Year
1988
Tongue
English
Weight
717 KB
Volume
4
Category
Article
ISSN
0742-2091

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✦ Synopsis


Barfknecht, Mecca and Naismith mammalian cell DNA, induced no detectable DNA repair in hepatocytes up to a toxic dose level of 2 X lO-SM with the 4 hour exposure period, whereas a marked DNA repair response was observed at lO-S M when the 18-20 hour exposure~labeling period was used.