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Effect of UV on cleavage of Xenopus laevis

✍ Scribed by Beal, Clayton M. ;Dixon, K. E.

Publisher: John Wiley and Sons
Year: 1975
Tongue: English
Weight: 380 KB
Volume: 192
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1401920218

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✦ Synopsis

Abstract

UV irradiation of the vegetal pole of stage 2 X. laevis embryos with doses of 6000–18000 ergs/mm^2^ delayed or inhibited cytokinesis in the vegetal hemisphere. Nuclear division continued so that a syncytium was formed, the size and persistence of which depended on the dose. Embryos which received a low UV dose were subsequently able to recover whereas embryos receiving a high dose were unable to gastrulate successfully. The implications for investigations into the role of cytoplasmic determinants are discussed.

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