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Effect of Turbulent Flow on Coil-Globule Transition of λ-DNA

✍ Scribed by Sung Taek Lim; Hyoung Jin Choi; Chi-Keung Chan

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
428 KB
Volume
26
Category
Article
ISSN
1022-1336

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✦ Synopsis

Abstract

Summary: The addition of spermidine (SPD) into turbulent flow as a condensing agent showed the abrupt change of turbulent drag reducing (DR) efficiency of λ‐DNA in turbulent flow for the first time. The resultant asymptote DR efficiency explains the origin of those changes, which can be conclusively verified via the electrophoresis experiment. Despite the different fluid conditions, with and without condensing agent, all λ‐DNA molecules possessed the same half‐cut dimension, implying that the discrete change of DNA conformation can dramatically alter the flow characteristics.

Coil‐globule transition of DNA by spermidine.

magnified imageCoil‐globule transition of DNA by spermidine.

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