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Effect of triamterene on folic reductase activity and reproduction in the rat

โœ Scribed by Alfred R. Maass; Virgil D. Wiebelhaus; Genevieve Sosnowski; Bernard Jenkins; George Gessner

Book ID
119000927
Publisher
Elsevier Science
Year
1967
Tongue
English
Weight
661 KB
Volume
10
Category
Article
ISSN
0041-008X

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Monitoring the effect of triamterene and hydrochlorothiazide on dihydrofolate reductase activity using a new spectrophotometric method
โœ Madiha B. Sidhom; Miriam R. Velez ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 407 KB

A new spectrophotometric method is developed and applied for the study of the inhibitory effect of triamterene, hydrochlorothiazide and their combinations on the in vitro activity of dihydrofolate reductase enzyme. The method is based on incubating the drug (0.1-1.0 microM) or a buffer control with