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Effect of treatment with difluoromethylornithine on polyamine and spectrin breakdown levels in neonatal rat brain

✍ Scribed by Imad Najm; Peter Vanderklish; Gary Lynch; Michel Baudry


Book ID
119101829
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
322 KB
Volume
63
Category
Article
ISSN
0165-3806

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✍ M. Sparapani; M. Virgili; M. Caprini; F. Facchinetti; E. Ciani; A. Contestabile πŸ“‚ Article πŸ“… 1996 πŸ› Springer-Verlag 🌐 English βš– 895 KB

Pregnant rats were treated for five consecutive days during gestation with s.c. injections of the ornithine decarboxylase (ODC) inhibitor alpha-difluoromethylornithine (DFMO). Treatment beginning at gestational days 13 or 14 was effective in inhibiting ODC and altering polyamine levels, and resulted