Effect of toremifene on the activity of NK-cells in NZB/NZW mice
✍ Scribed by Anni Wärri; Lauri Kangas
- Book ID
- 116007761
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 330 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0022-4731
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract NZB/NZW F~1~ female mice were treated with the immunosuppressive enzyme L‐asparaginase (Asnase) for up to 32 weeks. Asnase diminished circulating anti‐DNA and antinuclear antibodies, diminished deposition of γ‐globulins in kidneys, significantly delayed the onset of proteinuria, and red
## Proliferation of Ly-1 B cells in autoimmune NZB and (NZB X NZW)F1 mice* Spontaneous autoimmune disease in NZB and (NZB x NZW)FI (B/W) mice is associated with a spectrum of lymphoproliferative abnormalities, but the relationship between autoimmunity and lymphoproliferation is poorly understood.
## Objective: This study examined the interactions between exogenous and endogenous factors shaping the phenotype of lupus in autoimmune (nzb x nzw)f(1) mice exposed to pristane, a model environmental trigger. ## Methods: Frequencies of various autoantibodies in untreated nzb/nzw mice were determ