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Effect of topographical distribution of α-synuclein pathology on TDP-43 accumulation in Lewy body disease

✍ Scribed by Osamu Yokota; Yvonne Davidson; Tetsuaki Arai; Masato Hasegawa; Haruhiko Akiyama; Hideki Ishizu; Seishi Terada; Stephen Sikkink; Stuart Pickering-Brown; David M. A. Mann


Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
629 KB
Volume
120
Category
Article
ISSN
0001-6322

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To facilitate studies of the normal biology of ␣-synuclein, a member of a family of neuronal proteins of unknown function, and to elucidate the role of ␣-synuclein pathologies in neurodegenerative diseases, we generated and characterized a panel of anti-synuclein antibodies. Here we demonstrate that