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Effect of the ΔPhe residue configuration on a didehydropeptides conformation: A combined CD and NMR study

✍ Scribed by Marek Lisowski; Łukasz Jaremko; Mariusz Jaremko; Adam Mazur; Rafał Latajka; Maciej Makowski


Publisher
Wiley (John Wiley & Sons)
Year
2010
Tongue
English
Weight
527 KB
Volume
93
Category
Article
ISSN
0006-3525

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Combined effect of the ΔPhe or ΔAla resi
✍ M. Lisowski; R. Latajka; B. Picur; T. Lis; I. Bryndal; M. Rospenk; M. Makowski; 📂 Article 📅 2008 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 338 KB 👁 1 views

## Abstract Two series of dehydropeptides of the general formulae Boc‐Gly‐X‐Phe‐__p__‐NA, Boc‐Gly‐Gly‐X‐Phe‐__p__‐NA, Gly‐X‐Gly‐Phe‐__p__‐NA·TFA, and Boc‐Gly‐X‐Gly‐Phe‐__p__‐NA, with X = Δ^Z^Phe and ΔAla, were studied with NMR in DMSO and CDCl~3~‐DMSO, and with CD in MeOH, MeCN, and TFE. The NMR sp