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Effect of the V1a/V2-AVP receptor antagonist, Conivaptan, on renal water metabolism and systemic hemodynamics in rats with cirrhosis and ascites

✍ Scribed by Guillermo Fernández-Varo; Josefa Ros; Pilar Cejudo-Martı́n; Carmen Cano; Vicente Arroyo; Francisca Rivera; Juan Rodés; Wladimiro Jiménez


Book ID
118565979
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
329 KB
Volume
38
Category
Article
ISSN
0168-8278

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Hyponatremia in cirrhosis is associated with significant morbidity and mortality and complicates ascites management. Vasopressin receptor antagonists improve serum sodium concentration by increasing renal solute-free water excretion, but their effects on the management of ascites have not been asses