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Effect of the TP5 analogue of thymopoietin on the rejection of male skin by aged and thymectomized female mice

✍ Scribed by Ellen H. Goldberg; Gideon Goldstein; Edward A. Boyse; Margrit P. Scheid

Publisher: Springer-Verlag
Year: 1981
Tongue: English
Weight: 185 KB
Volume: 13
Category: Article
ISSN: 0093-7711
DOI: 10.1007/bf00350786

No coin nor oath required. For personal study only.

✦ Synopsis

Although young adult C3H/HeJ (C3H) females do not reject C3H male skin grafts, C3H females older than 1 year commonly do so, as also do many thymectomized, young adult C3H females. Therapy with TP5, a synthetic pentapeptide analogue of thymopoietin which has biological properties of the parent molecule, substantially reduced the capacity of aged C3H females and of thymectomized, young C3H females to reject C3H male skin.

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