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Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse

✍ Scribed by K. J. Jackson; Frank Ivy Carroll; S. S. Negus; M. I. Damaj


Publisher
Springer
Year
2010
Tongue
English
Weight
442 KB
Volume
210
Category
Article
ISSN
0033-3158

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The effect of acute and chronic nicotine treatment of rats on the mRNA levels coding for the three opioid peptide precursors, for provasopressin and for the c~3 subunit of nicotinic receptors in brain, pituitary and/or adrenal medulla of rats was investigated. Nicotine was found to increase the leve