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Effect of the rho-kinase inhibitor hydroxyfasudil on bladder overactivity: An experimental rat model

✍ Scribed by Toshihiko Masago; Takeshi Watanabe; Motoaki Saito; Yukako Kinoshita; Keisuke Sato; Ikuo Miyagawa

Book ID
108978029
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
223 KB
Volume
16
Category
Article
ISSN
0919-8172

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## Abstract ## Aims To investigate the concentration and activity of RhoA in detrusor and urothelium, as well as the effects of a Rho‐kinase inhibitor, Y‐27632 {(+)‐(R)‐trans‐4‐(1‐aminoethyl)‐N‐(4‐pyridyl) cyclohexanecarboxamide dihydrochloride}, on contraction of the pig urinary bladder. ## Meth