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Effect of the non-ionic surfactant Poloxamer 188 on passive permeability of poorly soluble drugs across Caco-2 cell monolayers

โœ Scribed by Sarah Maud Fischer; Martin Brandl; Gert Fricker


Book ID
116438490
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
342 KB
Volume
79
Category
Article
ISSN
0939-6411

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The effect of novel surfactants on the aqueous solubility and the permeability of paclitaxel across a Caco-2 cell monolayer were examined in this work. The solubility and permeability of paclitaxel was evaluated in the presence of four soft surfactants (SS) KXN441, KXN424, KXN437, and KXN 337 and So