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Effect of the Leaving Group and Solvent Combination on the LFER Reaction Constants

✍ Scribed by Matić, Mirela; Jurić, Sandra; Denegri, Bernard; Kronja, Olga


Book ID
120442144
Publisher
Molecular Diversity Preservation International
Year
2012
Tongue
English
Weight
333 KB
Volume
13
Category
Article
ISSN
1422-0067

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Quantum similarity approach to LFER: sub
✍ Robert Ponec; Lluís Amat; Ramon Carbó-Dorca 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 83 KB 👁 2 views

Quantum similarity measures were used to estimate dissociation constants for acid-base equilibria. It is proposed that the dissociation constant of a carboxylic acid may be described by the electronic density function of the COOH group and quantified by the self-similarity measure of this fragment.