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Effect of the intracellular Ca+2 antagonist TMB-8 on serum-stimulated Na+ influx in human fibroblasts

โœ Scribed by Nancy E. Owen; Mitchel L. Villereal


Book ID
115756234
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
373 KB
Volume
109
Category
Article
ISSN
0006-291X

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โœ Mitchel L. Villereal; Nancy E. Owen ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 872 KB

Stimulation of an amiloride-sensitive Na+ influx pathway, which mediates Na+/H+ exchange, has been postulated to be an important step in the initiation of DNA synthesis in quiescent human fibroblasts. If the elevation of intracellular Na+ or the alkalinization of intracellular pH resulting from the