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Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria☆☆☆★★★

✍ Scribed by Simons, F.Estelle R.; Sussman, Gordon L.; Simons, Keith J.


Book ID
119494879
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
765 KB
Volume
95
Category
Article
ISSN
1097-6825

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A possible interaction between the calcium antagonist nimodipine and the H2-receptor antagonists cimetidine and ranitidine has been investigated in two separate studies in healthy subjects. In eight young volunteers the concomitant administration of nimodipine 30 mg t.i.d. and cimetidine 1000 mg/d f