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Effect of the diterpene ester TPA on Epstein-Barr virus antigen- and DNA synthesis in producer and nonproducer cell lines

✍ Scribed by J. Hudewentz; G.W. Bornkamm; H. Zur Hausen

Book ID
119010206
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
268 KB
Volume
100
Category
Article
ISSN
0042-6822

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✍ Lajos Gergely; George Klein; Ingemar Ernberg πŸ“‚ Article πŸ“… 1971 πŸ› John Wiley and Sons 🌐 French βš– 651 KB

## Abstract The effect of two DNA antagonists (IUDR and Ara C) on EBV‐associated antigens was studied in two BL‐derived carrier culture lines (P3HR‐1 and Onesmas). Both drugs led to an accumulation of the early antigen (EA) from 2% in the untreated to 5–40% in the treated cultures. Ara C blocked th