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Effect of the degree of fatty acid unsaturation of rat heart mitochondria on their rates of H2O2 production and lipid and protein oxidative damage

✍ Scribed by Asunción Herrero; Manuel Portero-Otı́n; Marı́a Josep Bellmunt; Reinald Pamplona; Gustavo Barja


Book ID
114095997
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
190 KB
Volume
122
Category
Article
ISSN
0047-6374

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## Abstract In the present study, the question if medium‐term (4 months) caloric restriction (40%) decreases mitochondrial H~2~O~2~ production and oxidative DNA damage was investigated. Caloric restriction (CR) is the only experimental manipulation that increases maximum life span. Previous long‐te